Gene May Play A Role In Prostate Cancer Aggression
By Donna Parker • Apr 15th, 2010 • Category: Health News, Prostate health
Several physicians have touted the importance of older men getting their prostate-specific antigen (PSA) levels checked to ensure they’re not at risk for prostate cancer. Now, a new study is suggesting there may be a gene function that could leave patients more at risk.
According to researchers from the University of Texas (UT) Southwestern Medical Center, prostate cancer cells can be held in check by a DAB2IP gene, which can ensure that the disease stays under control. However, if the gene loses its function, these cancer cells are released into the body, which could lead to a more aggressive and potentially life-threatening cancer.
The scientists studied mice, shutting off the gene at first, and then restoring the function, noting the progression of the cancer and how the restoration helped protect the body from the cancer spreading.
"Cells undergoing an epithelial to mesenchymal transition (EMT) experience biological changes that enable them to move freely and spontaneously throughout the body," said senior author Jer Tsong Hsieh Ph.D. "By restoring DAB2IP function in cancer cells in mice, we reversed their ability to change and metastasize."
What doctors aren’t telling you about popular prostate drugs
These days, doctors prescribe prostate drugs by the boatload. But they don’t always tell you about the nasty side effects. For example, did you know that Proscar® can:
- Create deceptively positive results on your PSA tests…
- Increase the risk of abnormal cell growth in your prostate…
- Cause birth defects if your sexual partner is pregnant…
- Trigger low sex drive, premature ejaculation and impotence…
- And more!
Don’t let your doctor lead you down the wrong path, even if they’re doing it unwittingly. Protect your prostate naturally…

Donna Parker
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